What is aspergillosis?
Aspergillosis is an infection or allergic reaction caused by aspergillus — a mold (fungus) found in the environment, such as in decaying vegetation and household dust. In healthy individuals, it rarely causes problems. But aspergillus may affect people with asthma or weakened immune systems.
An aspergillus skin test can determine whether someone has been exposed to aspergillus. It's performed by injecting an aspergillus antigen under the skin. Inflammation at the injection site indicates past exposure to aspergillus.
Aspergillus can cause illness in several ways, including:
ABPA is an allergic lung reaction that often mimics pneumonia. Signs and symptoms include:
A doctor may make a diagnosis of ABPA by:
Treatment may include oral prednisone.
Signs and symptoms of invasive pulmonary aspergillosis include:
The infection can spread to other organs, such as the skin, eyes, heart, brain and kidneys. Diagnosis and treatment are difficult. A doctor may suspect invasive pulmonary aspergillosis based on a chest X-ray or CT scan or by a sputum stain and culture. A diagnosis may be confirmed by a biopsy of infected tissue. Treatment usually includes antifungal medications.
Last Updated: 06/15/2006
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