What is polycythemia vera?
Polycythemia vera is a rare blood disorder in which the bone marrow makes too many red blood cells and occasionally too many white blood cells and platelets. This interferes with normal blood flow, which can lead to blood clots, heart attacks or strokes. The cause of polycythemia vera isn't known. But other causes of an increased red blood cell count include smoking, living at a high altitude and congenital heart conditions.
Polycythemia vera occurs most often in older adults. The disease usually develops slowly. Many people have no symptoms for years. Others may experience nonspecific symptoms, such as:
Because polycythemia vera initially causes no signs or symptoms, it is often found incidentally on blood tests done for some other reason.
There is no cure for polycythemia vera. Treatment is directed at reducing the number of red blood cells and controlling signs and symptoms. Treatment may include:
Most people with polycythemia vera live for many years with proper medical care. However, polycythemia may lead to acute myelogenous leukemia.
Last Updated: 11/15/2005
© 1998-2016 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "Mayo Clinic Health Information," "Reliable information for a healthier life" and the triple-shield Mayo logo are trademarks of Mayo Foundation for Medical Education and Research.
Terms and conditions of use