Factor V deficiency: Is it inherited?

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Factor V deficiency: Is it inherited?

Question

Is factor V deficiency inherited? How is it treated?

Lynda
No state given

Answer

Factor V deficiency — sometimes called parahemophilia X — is a rare, inherited bleeding disorder. It's caused by inadequate levels of clotting factor V due to a gene defect. This defect is inherited in an autosomal recessive manner. This means a child must inherit two defective genes — one from each parent — to develop the disease.

A deficiency of factor V delays or slows clotting and can result in excessive bleeding. Bleeding can range from mild to severe and may include:

  • Bleeding into the skin
  • Easy bruising
  • Nosebleeds
  • Excessive menstrual bleeding
  • Excessive bleeding with surgery or injury
  • Bleeding of the gums

A doctor can confirm a diagnosis of factor V deficiency by special blood tests. There's no cure for this disorder. Blood transfusions temporarily correct the deficiency. During bleeding episodes, blood transfusions may be needed daily.

Last Updated: 09/20/2006
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