Factor V deficiency: Is it inherited?

content provided by mayoclinic.com

Factor V deficiency: Is it inherited?


Is factor V deficiency inherited? How is it treated?

No state given


Factor V deficiency — sometimes called parahemophilia X — is a rare, inherited bleeding disorder. It's caused by inadequate levels of clotting factor V due to a gene defect. This defect is inherited in an autosomal recessive manner. This means a child must inherit two defective genes — one from each parent — to develop the disease.

A deficiency of factor V delays or slows clotting and can result in excessive bleeding. Bleeding can range from mild to severe and may include:

  • Bleeding into the skin
  • Easy bruising
  • Nosebleeds
  • Excessive menstrual bleeding
  • Excessive bleeding with surgery or injury
  • Bleeding of the gums

A doctor can confirm a diagnosis of factor V deficiency by special blood tests. There's no cure for this disorder. Blood transfusions temporarily correct the deficiency. During bleeding episodes, blood transfusions may be needed daily.

Last Updated: 09/20/2006
© 1998-2016 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "Mayo Clinic Health Information," "Reliable information for a healthier life" and the triple-shield Mayo logo are trademarks of Mayo Foundation for Medical Education and Research.

Terms and conditions of use


Bookmark and Share   E-Mail Page   Printer Friendly Version