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Diuretics: A cause of low potassium?

content provided by mayoclinic.com

Diuretics: A cause of low potassium?

Question

I have high blood pressure and take several medications for it, including a diuretic and an ACE inhibitor. Even though I take potassium supplements, my doctor says my potassium level is too low. What causes this?

Jan
Nebraska

Answer

Many diuretics decrease potassium in the blood. Diuretics lower blood pressure by helping your body eliminate sodium and water. This reduces blood volume and helps decrease pressure on your artery walls. When your body excretes excessive amounts of water, it also loses extra potassium. This can lead to low potassium levels in your blood (hypokalemia).

There are potassium-sparing diuretics that don't cause this problem. These include:

  • Spironolactone (Aldactone)
  • Eplerenone (Inspra)
  • Triamterene (Dyrenium)
  • Amiloride (Midamor)

Angiotensin-converting enzyme (ACE) inhibitors reduce blood pressure by helping to relax blood vessels. ACE inhibitors usually increase potassium levels in your blood.

If you're taking an ACE inhibitor and getting enough potassium in your diet but still have low potassium, your doctor may recommend further testing to help identify the underlying cause. Rarely, low potassium may be due to overproduction of the hormone aldosterone (hyperaldosteronism), which increases potassium loss by the kidneys.

Treatment of low potassium may include:

  • Increasing potassium in your diet
  • Use of potassium supplements
  • Changing to a potassium-sparing diuretic

Last Updated: 07/26/2005
© 1998-2006 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "Mayo Clinic Health Information," "Reliable information for a healthier life" and the triple-shield Mayo logo are trademarks of Mayo Foundation for Medical Education and Research.

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