Hoodia: An effective appetite suppressant?

There is no conclusive evidence that hoodia is an effective appetite suppressant or that it contributes to significant, long-term weight loss. Hoodia is a cactus that is native to the Kalahari Desert in Africa. Natives supposedly eat it to reduce hunger during long hunts, which led to interest in hoodia as a possible weight-loss aid.

One small study — sponsored by a supplement manufacturer — found that hoodia may affect the part of the brain that controls hunger. But much more research is needed to establish the potential effectiveness and long-term safety of hoodia.