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High cholesterol: Does it increase my risk of Alzheimer's?

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High cholesterol: Does it increase my risk of Alzheimer's?

Question

What is the role of cholesterol in Alzheimer's disease? Does having high cholesterol increase my risk of Alzheimer's?

Dean
Maryland

Answer

There is very little evidence to indicate that a high blood level of cholesterol has any bearing on the risk of Alzheimer's disease. Although a few studies have made this claim, the vast majority of research has found no link between high cholesterol and Alzheimer's.

Several clinical trials are under way to determine if cholesterol-lowering drugs can prevent or delay Alzheimer's disease. But such drugs are not being tested in people with elevated cholesterol levels. Instead, it appears that some cholesterol-lowering drugs may coincidentally affect a process that increases the risk of Alzheimer's — unrelated to their effect on cholesterol.

It's premature at this time to recommend cholesterol treatment to prevent Alzheimer's. More research is needed to clarify whether cholesterol medications may play a role in preventing or treating Alzheimer's.

Last Updated: 11/27/2007
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